Author

Laina Freyer

Centre National de la Recherche ScientifiqueORCID 0000-0002-1997-4150Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Elisa Gomez PerdigueroiD· 3 shared Ana CumanoiD· 2 shared Francisca Soares‐da‐SilvaiD· 2 shared Ramy ElsaidiD· 2 shared Alina SommeriD· 1 shared António BandeiraiD· 1 shared Archibald S. PerkinsiD· 1 shared Gonçalo NogueiraiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Elisa Gomez PerdigueroORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Ontogeny drives stage-specific effects of a Gata1 mutation

Alina Sommer, Stephan Fischer, Laina Freyer, Yvan Lallemand, Pascal Dardenne, Elisa Gomez Perdiguero

The paper shows that a Gata1 mutation affects megakaryocyte development differently in fetal and adult stages due to distinct progenitor origins.

bioRxiv · Jan 15, 2025 · PreprintDevelopmental Biology

Distinct origin and fate for fetal hematopoietic progenitors

Francisca Soares‐da‐Silva, Gonçalo Nogueira, Marie-Pierre Mailhé, Laina Freyer, Archibald S. Perkins, Shinya Hatano, Yasunobu Yoshikai, Pablo Pereira, António Bandeira, Ramy Elsaid, Elisa Gomez Perdiguero, Ana Cumano

The paper identifies distinct roles for embryonic multipotent progenitors (eMPP) and hematopoietic stem cells (HSC) in fetal hematopoiesis and immune system development.

bioRxiv · Jan 8, 2025 · PreprintDevelopmental Biology

Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life

Francisca Soares‐da‐Silva, Laina Freyer, Ramy Elsaid, Odile Burlen‐Defranoux, Lorea Iturri, Odile Sismeiro, Perpétua Pinto‐do‐Ó, Elisa Gomez Perdiguero, Ana Cumano

This study shows yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life by outcompeting hematopoietic stem cell-derived progenitors in low erythropoietin environments.

The Journal of Experimental Medicine · Jan 8, 2021Peer-reviewedDevelopmental Biology