Perpétua Pinto‐do‐Ó

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

This study shows FLT3 is essential for ITD-mutated leukemic stem cells but not for normal hematopoietic stem cells, supporting targeted therapies for AML.

Spatiotemporal dynamics of cytokines expression dictate fetal liver hematopoiesis.

The paper identifies the spatiotemporal dynamics of cytokine expression in fetal liver hematopoiesis, showing that hepatoblasts and mesothelial cells produce key growth factors and cytokines.

Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life

This study shows yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life by outcompeting hematopoietic stem cell-derived progenitors in low erythropoietin environments.

HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury

The paper identifies HSA/CD24+ immature cardiomyocytes that persist in adult hearts and expand after ischemic injury.