Author

Lei Dong

State Key Laboratory of Pharmaceutical BiotechnologyORCID 0000-0002-2013-4191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Anheng WangiD· 1 shared Chengwu LiiD· 1 shared Chunhao Deng· 1 shared Chunli YangiD· 1 shared Chunming WangiD· 1 shared Guokai CheniD· 1 shared jiaxian wang· 1 shared Qian WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Anheng WangORCID

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1 paper

Recent·Most cited

Dissecting organoid-bacteria interaction highlights decreased contractile force as a key factor for heart infection

Anheng Wang, jiaxian wang, Zhe Zhang, Chunli Yang, Chunhao Deng, Guokai Chen, Chengwu Li, Qian Wang, Lei Dong, Chunming Wang

The paper uses a physics model to show weakened heart contractility increases bacterial invasion risk in cardiac organoids, with mouse experiments confirming a 80% reduction in endocarditis risk with increased contractility.

bioRxiv · Apr 8, 2025 · PreprintBioengineering