Chunli Yang

The paper shows that enhanced ERK signaling in human cortical radial glia drives cortical neuron expansion through interactions with PKA signaling and cell cycle regulation.

This paper shows that FGFR3 mutations cause bone shortening and brain overgrowth through ERK-mediated self-repression in different tissues.

This study identifies how ERK, PKA, YAP/TAZ, and SHH signaling integrate to drive cortical lineage diversification and evolutionary expansion in the human cerebral cortex.

The paper uses a physics model to show weakened heart contractility increases bacterial invasion risk in cardiac organoids, with mouse experiments confirming a 80% reduction in endocarditis risk with increased contractility.