Taylor R. Cole

This study compares the dynamic properties of IL-1β and IL-1Ra using NMR relaxation to show that their distinct functional roles in IL-1R signaling arise from differences in conformational entropy at the receptor interface.

This paper develops an algorithm to automate cross-peak matching between multidimensional NMR spectra by modeling deviations as a distribution of noise and true shifts, using Bayesian inference to provide confidence estimates.