Waleed S. Albihlal

Yeast m6A reader Pho92 uses one helical hydrophobic interface in its disordered region to engage Caf40; a single L35A substitution halts m6A-transcript decay in meiosis.

This study identifies Pfk2p as an ATP-dependent RNA unwinding enzyme that modulates cell cycle progression by promoting translation of mitotic genes.

The paper identifies three novel components of the yeast m6A methyltransferase complex and reveals their distinct m6A-dependent and independent roles in meiosis and mating.