Author

Ana Casañal

Human TechnopoleORCID 0000-0002-0334-0591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

Michelangelo LassandroiD· 2 shared Alessio Di IanniiD· 1 shared Alexander Maman· 1 shared Alice RossiiD· 1 shared Ambrosius P. SnijdersiD· 1 shared Andrea GraziadeiiD· 1 shared Arianna Di FazioiD· 1 shared Elodie Carmen LeroyiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Michelangelo LassandroORCID

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2 papers

Recent·Most cited

Molecular basis of tRNA modification by the human m5C methyltransferase NSUN2

Elodie Carmen Leroy, Michelangelo Lassandro, Arianna Di Fazio, Alessio Di Ianni, Kanhaya Lal, Jon Rodriguez-Villa, Alice Rossi, Andrea Graziadei, Monika Gullerová, Ana Casañal

This study determines the structure of the NSUN2-tRNA complex and reveals how NSUN2 recognizes and modifies tRNA through RNA architecture and specific amino acid interactions.

bioRxiv · Mar 18, 2026 · PreprintMolecular Biology

The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles

Imke Ensinck, Alexander Maman, Waleed S. Albihlal, Michelangelo Lassandro, Giulia Salzano, Theodora C. Sideri, Steven A. Howell, Enrica Calvani, Harshil Patel, G. Guy Bushkin, Markus Ralser, Ambrosius P. Snijders, Mark J. Skehel, Ana Casañal, Schraga Schwartz, Folkert Jacobus van Werven

The paper identifies three novel components of the yeast m6A methyltransferase complex and reveals their distinct m6A-dependent and independent roles in meiosis and mating.

eLife · Jun 1, 2023Peer-reviewedMolecular Biology