MicrobiologybioRxivPreprint
Establishment of a Long-Term Germ-Free Medaka Model Reveals Microbiota-Dependent Regulation of Growth, Immunity, and Metabolism
Pan‐Pan Jia, Mingfei Wu, Liping Ma…·De‐Sheng Pei
This study establishes a long-term germ-free medaka model to investigate microbiota-dependent effects on growth, immunity, and metabolism, finding that gut-derived metabolites partially restore developmental and immune deficits but not long-term survival.
DOI 10.64898/2026.03.09.710661