Yu Chen

Unveiling the PHR-centered regulatory network orchestrating the phosphate starvation signaling in Chinese fir (Cunninghamia lanceolata)

This study identifies ClPHRs as key regulators of phosphate starvation signaling in Chinese fir, revealing evolutionary differences in the SPX-PHR module compared to model plants.

Chinese fir genome and the evolution of gymnosperms

The paper presents the genome of Chinese fir, revealing evolutionary insights into gymnosperms and seed plant origins through phylogenomic and genomic analyses.

High coverage whole genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios

The paper presents a high coverage whole genome sequencing resource of 3,202 samples, including 602 trios, generated from the expanded 1000 Genomes Project.

SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data

SCReadCounts estimates cell-level SNVs from scRNA-seq data, enabling mutation analysis and downstream applications in cancer and other studies.

De novo assembly of 64 haplotype-resolved human genomes of diverse ancestry and integrated analysis of structural variation

The paper presents 64 haplotype-resolved human genomes using long-read sequencing and identifies structural variants, SV-eQTLs, and adaptive selection candidates.

Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression

The paper develops a quality control-based random forest regression method to correct signal drift in metabolomics and proteomics data, improving precision and statistical accuracy.