Zongwei Cai

Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution

This paper introduces a novel MALDI-MSI method achieving 500 nm resolution for subcellular imaging in mouse brain tissues and cultured cells.

Rewired NAD+ metabolism promotes NF-κB-mediated oxidative stress and disrupts lipid homeostasis in liver fibrosis progression

This study identifies NAD+ metabolism rewiring as a key driver of oxidative stress and lipid dysregulation in liver fibrosis progression using multi-omics analyses in a mouse model.

A Newborn F-box Gene Blocks Gene Flow by Selectively Degrading Phosphoglucomutase in Species Hybrids

This paper shows a new F-box gene in C. nigoni causes hybrid incompatibility by degrading a phosphoglucomutase from C. briggsae, leading to embryonic death in hybrids.

Single-Cell Resolution DESI Mass Spectrometry Imaging through 10-Fold Sample Expansion

This paper introduces 10x-DESI ExMSI, a technique that expands tissue samples to achieve single-cell resolution in DESI MSI without altering mass spectrometers.

TagSeqTools: a flexible and comprehensive analysis pipeline for NAD tagSeq data

TagSeqTools is a pipeline for analyzing NAD tagSeq data to identify and quantify NAD+-capped RNAs using Oxford Nanopore long-read sequencing.

Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression

The paper develops a quality control-based random forest regression method to correct signal drift in metabolomics and proteomics data, improving precision and statistical accuracy.