Author

Daniela Ledezma-Tejeida

ETH ZurichORCID 0000-0002-2055-417XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro Aguilar-VeraiD· 1 shared David HidalgoiD· 1 shared José Arcadio Farías‐RicoiD· 1 shared José UtrillaiD· 1 shared Julio Collado‐VidesiD· 1 shared Lizeth Soto-Avila· 1 shared Luis Altamirano‐PachecoiD· 1 shared Vicente FajardoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperSystems Biology

Alejandro Aguilar-VeraORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintAug 18, 2026

Potential benefit of loss-of-function on bacterial fitness

David Hidalgo, Lizeth Soto-Avila, Alejandro Aguilar-Vera…·José Utrilla

This study investigates how gene loss affects bacterial fitness in E. coli by analyzing proteomic data and identifying gene categories with varying fitness impacts.

DOI 10.64898/2026.08.13.744710

E. coliproteomics

𝕏 PostBluesky

BioinformaticsNucleic Acids ResearchPeer-reviewedJun 4, 2019

Limits to a classic paradigm: Most transcription factors regulate genes in multiple biological processes

Daniela Ledezma-Tejeida, Luis Altamirano‐Pacheco, Vicente Fajardo, Julio Collado‐Vides

The paper shows that most transcription factors regulate genes involved in multiple biological processes, challenging the one TF/one process assumption.

14 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky