Luis Altamirano‐Pacheco

This study identifies MYC and MAX as critical for post-mitotic genome reactivation in pluripotent mouse embryonic stem cells, showing MAX's role in bookmarking and MYC recruitment.

This study maps positive DNA supercoiling across interphase and mitosis, revealing its role in transcriptional control and genome architecture.

The paper shows that most transcription factors regulate genes involved in multiple biological processes, challenging the one TF/one process assumption.