José Utrilla

This study investigates how gene loss affects bacterial fitness in E. coli by analyzing proteomic data and identifying gene categories with varying fitness impacts.

This paper maps gene essentiality in Pseudomonas chlororaphis using transposon mutagenesis and integrates functional annotations to identify essential pathways and non-essential regions.

This study engineers E. coli to produce ornithine lipids, improving stress resistance and biomass yield under phosphate limitation and low pH conditions.

The paper shows that reducing ribosomal RNA operons or mutating rpoB in E. coli increases growth rate but reduces hedging functions and adaptation capacity.

This paper introduces a method to reduce proteome allocation in E. coli through minimal genetic interventions, improving recombinant production yield.