Author

Kevin Yang Zhang

Johns Hopkins UniversityORCID 0000-0002-2074-6876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Ashish BhandariiD· 2 shared Donald J. ZackiD· 2 shared Harry A. QuigleyiD· 2 shared JENNIE SMITHiD· 2 shared Matthew J. Van HookiD· 2 shared Sarah E. QuilleniD· 2 shared Thomas V. JohnsoniD· 2 shared Aaron A. JenseniD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Ashish BhandariORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Internal limiting basement membrane inhibits functional engraftment of transplanted human retinal ganglion cells

Erika A. Aguzzi, Stella Mary, Marzieh Mowlavi Vardanjani, Dayn R. Godinez, Elizabeth C. Kimball, Behnoosh Bonakdar, Kevin Yang Zhang, Jian Du, Arumugam Nagalingam, William H. Yutzy, Sarah E. Quillen, Shreya L. Hariharakumar, Harry A. Quigley, Donald J. Zack, James T. Handa, Thomas V. Johnson

This study shows that disrupting the internal limiting membrane enhances the survival and functional integration of transplanted human retinal ganglion cells in the retina.

Science Translational Medicine · Apr 29, 2026Peer-reviewedNeuroscience

Clinical and molecular features of primary gliosarcoma with digital spatial whole-transcriptome analysis of glial and mesenchymal components

Matthew D. Wood, Gabriel Mesquita Zangirolani, Jinho Lee, Melanie H. Hakar, Tanaya L. Neff, Kevin Yang Zhang, Christopher L. Corless

This study analyzes gliosarcoma using digital spatial transcriptomics to compare glial and mesenchymal components with glioblastoma, identifying genetic and transcriptomic differences.

Brain Pathology · Mar 18, 2026Peer-reviewedPathology

Loss of retinogeniculate synaptic function in the DBA/2J mouse model of glaucoma.

JENNIE SMITH, Kevin Yang Zhang, Asia L. Sladek, Jennifer Thompson, Elizabeth R. Bierlein, Ashish Bhandari, Matthew J. Van Hook

This study examines how glaucoma affects retinal ganglion cell (RGC) signaling to the dLGN in DBA/2J mice, finding functional deficits linked to intraocular pressure.

eNeuro · Nov 1, 2022Peer-reviewedNeuroscience

Structural engraftment and topographic spacing of transplanted human stem cell-derived retinal ganglion cells

Kevin Yang Zhang, Caitlyn Tuffy, Joseph L. Mertz, Sarah E. Quillen, Laurence Wechsler, Harry A. Quigley, Donald J. Zack, Thomas V. Johnson

This study investigates how transplanted human stem cell-derived retinal ganglion cells integrate into the host retina and identifies the internal limiting membrane as a barrier to structural integration.

Stem Cell Reports · Dec 30, 2020Peer-reviewedNeuroscience

Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus

Ashish Bhandari, JENNIE SMITH, Kevin Yang Zhang, Aaron A. Jensen, Lisa Reid, Toni Goeser, Shan Fan, Deepta A Ghate, Matthew J. Van Hook

This study shows that early-stage ocular hypertension causes pre- and post-synaptic functional and structural changes at retinogeniculate synapses before significant RGC loss.

Frontiers in Cellular Neuroscience · Sep 19, 2019Peer-reviewedNeuroscience