Chunwei Zheng

This paper demonstrates that a compact ABE corrects the PiZ mutation in AATD mouse models, reducing liver disease and improving lung function.

The paper shows miR-202 prevents premature spermatogonial differentiation and meiotic initiation in mice by regulating genes like DMRT6 and STRA8.

This study develops a compact prime editor with reduced reverse transcriptase activity, showing efficient editing and enabling flexible split-PE design for in vivo delivery.

This study identifies miR-202 as a regulator of meiosis in mice by preventing premature degradation of REC8 via separase inhibition.