Author

Mary E.W. Collier

University of LeicesterORCID 0000-0002-2088-4013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Flaviano GiorginiiD· 4 shared Nicolas B. SylviusiD· 3 shared Donald J. L. JonesiD· 2 shared Elliot L. Hong· 2 shared Jordan Cassidy· 2 shared Joshua ChiappelliiD· 2 shared Natalie AllcockiD· 2 shared Robert M. SchwarcziD· 2 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersCell Biology

Flaviano GiorginiORCID

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5 papers

Recent·Most cited

Cell BiologyPLoS ONEPeer-reviewedJun 26, 2026

Proteomic analysis of extracellular vesicles released from endothelial cells in vitro reveals increased levels of E-selectin and dual specificity phosphatase 7 as a potential marker of TNFα-mediated apoptosis

Mary E.W. Collier, Thong Huy Cao, Paulene A. Quinn…·Alison H. Goodall

This study identifies E-selectin and dual specificity phosphatase 7 as differentially expressed proteins in TNFα-stimulated endothelial cell extracellular vesicles, suggesting their potential as biomarkers for endothelial apoptosis in cardiovascular disease.

DOI 10.1371/journal.pone.0352394

humanproteomics

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Molecular BiologybioRxivPreprintMay 21, 2026

The single nucleotide polymorphism rs1053230 modulates kynurenine 3-monooxygenase stability and is associated with cognitive and mood phenotypes

Mary E.W. Collier, Georgia Ceeney, Joshua Chiappelli…·Flaviano Giorgini

This study investigates the functional impact of SNPs rs1053230 and rs2275163 on KMO protein stability and interactions, linking rs1053230 to depressive mood symptoms.

DOI 10.64898/2026.05.19.726163

humanexperimental assay

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Cell BiologybioRxivPreprintMay 13, 2026

Physiological levels of 3-hydroxykynurenine alter mitochondrial function and morphology in neuronal cells

Jordan Cassidy, Mary E.W. Collier, Flaviano Giorgini

This study investigates the effects of physiological levels of 3-hydroxykynurenine on mitochondrial function and morphology in neuronal cells, revealing biphasic changes and potential implications for neurodegenerative diseases.

DOI 10.64898/2026.05.13.724856

humanbulk RNA-seq

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GeneticsbioRxivPreprintMar 6, 2026

Identification of a miRNA signature for schizophrenia in plasma-derived extracellular vesicles

Mary E.W. Collier, Joshua Chiappelli, Hollie Marshall…·Flaviano Giorgini

The paper identifies a miRNA signature in plasma-derived extracellular vesicles associated with schizophrenia and links one miRNA to working memory and white matter integrity.

DOI 10.64898/2026.03.06.710021

humanstatistical model

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Cell BiologyBMC MethodsPeer-reviewedJun 30, 2025

Examination of the enrichment of neuronal extracellular vesicles from cell conditioned media and human plasma using an anti-NCAM immunocapture bead approach

Mary E.W. Collier, Natalie Allcock, Nicolas B. Sylvius…·Flaviano Giorgini

This paper evaluates an anti-NCAM immunocapture method for enriching neuronal extracellular vesicles from cell media and plasma, finding it effective for cultured EVs but limited in plasma due to low nEV levels.

12 citations

humanspatial transcriptomics

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