Paulene A. Quinn

Proteomic analysis of extracellular vesicles released from endothelial cells in vitro reveals increased levels of E-selectin and dual specificity phosphatase 7 as a potential marker of TNFα-mediated apoptosis

This study identifies E-selectin and dual specificity phosphatase 7 as differentially expressed proteins in TNFα-stimulated endothelial cell extracellular vesicles, suggesting their potential as biomarkers for endothelial apoptosis in cardiovascular disease.

The Multiomics Blueprint of Extreme Human Lifespan

This study presents a multi-omics analysis of a supercentenarian, revealing that extreme age and poor health are distinct molecular processes.

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.

The paper identifies molecular and metabolic signatures of cardiometabolic syndrome using extreme phenotype groups and shows changes after bariatric surgery.