Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1
Alba Muniesa-Vargas, Cristina Ribeiro-Silva, Bart Geverts, Carlota Davó-Martínez, Jacinta van de Grint, Maroussia M. P. Ganpat, Karen L. Thijssen, Joris Pothof, Adriaan B. Houtsmuller, Arjan F. Theil, Wim Vermeulen, Hannes Lans
This study investigates how XPG function is regulated during nucleotide excision repair through dynamic interactions with TFIIH, XPA, and EXO1, revealing mechanisms of XPG recruitment and dissociation from DNA damage.
bioRxiv · Dec 6, 2024 · PreprintGenetics