Manfredi Castelli

A shared manifold for scalable temporal representations in self-paced timing

The paper shows that brain regions use a shared ring manifold to represent time, with population activity evolving along a common trajectory to encode elapsed time through traversal speed modulation.

Hippocampal Ripple Diversity organises Neuronal Reactivation Dynamics in the Offline Brain

The paper identifies two distinct hippocampal ripple types in mice during sleep/rest, showing they reorganize neuronal reactivation differently to integrate recent experiences and update prior memories.

Offline hippocampal reactivation during dentate spikes supports flexible memory

This study shows that dentate spikes (DSs) during sleep reactivate memory-related neuronal patterns, supporting flexible memory, and are distinct from sharp-wave ripples (SWRs) in their structure and function.