Author

Bertrand De Meulder

European Institute for Systems Biology and MedicineORCID 0000-0002-2108-7657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Charles AuffrayiD· 2 shared Francesco MessinaiD· 2 shared Adrien RougnyiD· 1 shared Ahmed Abdelmonem HemedaniD· 1 shared Akira FunahashiiD· 1 shared Alberto ValdeolivasiD· 1 shared Alessandra D’AbramoiD· 1 shared Alessandro CaponeiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Charles AuffrayORCID

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Author profile →

3 papers

Recent·Most cited

A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms

Anna Niarakis, Marek Ostaszewski, Alexander Mazein, Inna Kuperstein, Martina Kutmon, Marc E. Gillespie, Akira Funahashi, Márcio Luís Acencio, Ahmed Abdelmonem Hemedan, Michael Aichem, Karsten Klein, Tobias Czauderna, Felicia Burtscher, Takahiro Yamada, Yusuke Hiki, , the COVID-19 Disease Map Community

The paper presents a computational framework for analyzing SARS-CoV-2-host interactions to identify drug targets and model disease mechanisms.

bioRxiv · Dec 17, 2022 · PreprintSystems Biology

Morse-clustering of a Topological Data Analysis Network Identifies Phenotypes of Asthma Based on Blood Gene Expression Profiles

James P R Schofield, Fabio Strazzeri, Jeannette Bigler, Michael Boedigheimer, Ian M Adcock, Kian Fan Chung, Aruna Bansal, Richard G. Knowles, Sven-Erik Dahlen, Craig E. Wheelock, Kai Sun, Ioannis Pandis, John Riley, Charles Auffray, Bertrand De Meulder, , Paul J Skipp

The paper uses a discrete Morse theory clustering algorithm on a TDA network of gene expression data to identify nine molecular phenotypes associated with asthma and glucocorticoid receptor signaling differences.

bioRxiv · Jun 22, 2020 · PreprintMolecular Biology

COVID-19: Viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection.

Francesco Messina, Emanuela Giombini, Chiara Agrati, Francesco Vairo, Tommaso Ascoli Bartoli, Samir Al Moghazi, Mauro Piacentini, Franco Locatelli, Gary Kobinger, Markus J. Maeurer, Alimuddin I. Zumla, Maria Rosaria Capobianchi, F. Lauria, Giuseppe Ippolito, COVID 19 INMI Network Medicine for IDs Study Group, , Nicola Segata

The paper analyzes the viral-host interactome of SARS-CoV, MERS-CoV, and HCoV-229E using a network-based approach to predict SARS-CoV-2 pathogenesis.

Journal of Translational Medicine · Jun 10, 2020Peer-reviewedBioinformatics