Philippa L. Steinberg

Metapipeline-DNA automates comprehensive analysis of DNA sequencing data from raw reads to visualization, supporting germline and somatic genomic features.

A sequencing-based neutralization assay across 78 H3N2 HA strains and 150 sera shows strain growth in 2023 tracks the fraction of sera with low titers, but not pooled-serum titers.

This study demonstrates that RNA transcripts can serve as templates for double-strand break repair in human cells, identifying DNA polymerase-zeta as a key enzyme and revealing genomic scars associated with this process.

This study evaluates how different random seeds affect subclonal reconstruction algorithms in cancer genomics, finding significant variability in subclone estimates across seeds.

This study quantifies how aging and genetics influence gene expression across 27 human tissues, finding tissue-specific differences in their contributions and identifying signatures of aging and selection.