Specific detection and deletion of the Sigma-1 receptor in neurons and glial cells for functional characterization in vivo
Qing Liu, Qilin Guo, Li‐Pao Fang, Honghong Yao, Anja Scheller, Frank Kirchhoff, Wenhui Huang
This study develops a specific antibody and Cre-dependent conditional KO mouse to detect and delete the Sigma-1 receptor in specific cell types in vivo, revealing its widespread expression in neurons and glial cells.
Journal of Neurochemistry · Sep 9, 2022Peer-reviewedNeuroscience