Qilin Guo

Neuronal lysosome transfer to oligodendrocyte precursor cells: a novel mechanism of neuron-glia communication and its role in neurodegenerative disease

The paper identifies a novel neuron-glia communication mechanism where neurons transfer lysosomes to OPCs, linking this process to neurodegenerative disease progression.

Adenosine triggers early astrocyte reactivity that provokes microglial activation and drives the pathogenesis of sepsis-associated encephalopathy

This study shows that adenosine triggers early astrocyte reactivity in sepsis, leading to microglial activation and SAE pathogenesis.

Specific detection and deletion of the Sigma-1 receptor in neurons and glial cells for functional characterization in vivo

This study develops a specific antibody and Cre-dependent conditional KO mouse to detect and delete the Sigma-1 receptor in specific cell types in vivo, revealing its widespread expression in neurons and glial cells.