Author

Marı́a José De Rosa

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0002-2149-6127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Diego RayesiD· 3 shared Mark J. AlkemaiD· 2 shared Sebastián GiuntiiD· 2 shared Tania Veuthey· 2 shared Gabriela Blanco· 1 shared Jamie L. Donnelly· 1 shared Jeff Grant· 1 shared Jeremy FlormaniD· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Diego RayesORCID

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3 papers

Recent·Most cited

The ketone body β-hydroxybutyrate ameliorates neurodevelopmental deficits in the GABAergic system of daf-18/PTEN Caenorhabditis elegans mutants

Sebastián Giunti, María Gabriela Blanco, Marı́a José De Rosa, Diego Rayes

This study shows that β-hydroxybutyrate improves GABAergic neurodevelopment in daf-18/PTEN mutants by enhancing DAF-16/FOXO activity.

eLife · Oct 18, 2024Peer-reviewedNeuroscience

The neurohormone tyramine stimulates the secretion of an Insulin-Like Peptide from the intestine to modulate the systemic stress response in C. elegans

Tania Veuthey, Sebastián Giunti, Marı́a José De Rosa, Mark J. Alkema, Diego Rayes

This study identifies INS-3 as a key insulin-like peptide modulated by tyramine that influences stress resistance and reproductive development in C. elegans.

bioRxiv · Feb 6, 2024 · PreprintNeuroscience

Acute-stress impairs cytoprotective mechanisms through neural inhibition of the insulin pathway

Marı́a José De Rosa, Tania Veuthey, Jeremy Florman, Jeff Grant, Gabriela Blanco, Natalia Andersen, Jamie L. Donnelly, Diego Rayes, Mark J. Alkema

The paper shows that acute stress impairs cytoprotective mechanisms by inhibiting the insulin pathway through neural release of tyramine in C. elegans.

bioRxiv · Jun 30, 2018 · PreprintNeuroscience