Structure, function and variants analysis of the androgen-regulated TMPRSS2, a drug target candidate for COVID-19 infection
Alessia David, Tarun Khanna, Melina Beykou, Gordon Hanna, Michael J.E. Sternberg
The paper analyzes TMPRSS2 variants and their potential impact on SARS-CoV-2 infection, showing that some variants may affect protein structure and function, and that TMPRSS2 and ACE2 are co-expressed in the gastrointestinal tract.
bioRxiv · May 26, 2020 · PreprintBioinformatics