Michael J.E. Sternberg

The paper highlights discrepancies between AlphaFold predictions and UniProt data, showing how bioinformatics resources can quickly become outdated.

Missense3D-PPI predicts the impact of missense variants on protein-protein interfaces using structural data, showing improved sensitivity over previous methods.

This paper identifies a common TMPRSS2 variant that reduces the risk of severe COVID-19 by impairing SARS-CoV-2 entry into cells.

This study analyzes SARS-CoV-2 spike variants from Thailand, finding that novel variants do not significantly alter spike structure or ACE2 binding, and p.D614G became prevalent in the second outbreak.

The paper analyzes TMPRSS2 variants and their potential impact on SARS-CoV-2 infection, showing that some variants may affect protein structure and function, and that TMPRSS2 and ACE2 are co-expressed in the gastrointestinal tract.