Author

Tarun Khanna

Imperial College LondonORCID 0000-0003-4613-7531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessia DavidiD· 2 shared Michael J.E. SternbergiD· 2 shared Albert TenesaiD· 1 shared Aurélie CobatiD· 1 shared Erola Pairo‐CastineiraiD· 1 shared GenOMICC Investigators· 1 shared Gordon Hanna· 1 shared ISARIC4C Investigators· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alessia DavidORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineCurrent Research in Translational MedicinePeer-reviewedJan 10, 2022

A common TMPRSS2 variant protects against severe COVID-19

Alessia David, Nick Parkinson, Thomas P. Peacock…·Michael J.E. Sternberg

This paper identifies a common TMPRSS2 variant that reduces the risk of severe COVID-19 by impairing SARS-CoV-2 entry into cells.

54 citationstop 2%

humanGWAS summary statistics

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BioinformaticsbioRxivPreprintMay 26, 2020

Structure, function and variants analysis of the androgen-regulated TMPRSS2, a drug target candidate for COVID-19 infection

Alessia David, Tarun Khanna, Melina Beykou…·Michael J.E. Sternberg

The paper analyzes TMPRSS2 variants and their potential impact on SARS-CoV-2 infection, showing that some variants may affect protein structure and function, and that TMPRSS2 and ACE2 are co-expressed in the gastrointestinal tract.

7 citations

humanDNA methylation

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