Author

Gordon Hanna

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:variant effect prediction· 3 Organism:human· 2 Assay:protein structure· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alessia DavidiD· 3 shared Michael J.E. SternbergiD· 2 shared Suhail A. IslamiD· 2 shared Cecilia PennicaiD· 1 shared Gemma WalkeriD· 1 shared Haotian ZhaoiD· 1 shared Ifigenia TsitsaiD· 1 shared Melina BeykouiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBioinformatics

Alessia DavidORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Missense3D-PTMdb an interactive web resource to explore and visualize genetic variants and post-translational modifications sites (PTMs) using AlphaFold 3D models

Haotian Zhao, Ryan Pye, Gemma Walker, Wendy Tran, Olivia Simmonds, Ifigenia Tsitsa, Suhail A. Islam, Gordon Hanna, Alessia David

Missense3D-PTMdb maps missense variants and PTM sites to AlphaFold 3D models to explore their structural and functional impacts.

bioRxiv · Jul 22, 2025 · PreprintGenetics

A new web resource to predict the impact of missense variants at protein interfaces using 3D structural data: Missense3D-PPI

Cecilia Pennica, Gordon Hanna, Suhail A. Islam, Michael J.E. Sternberg, Alessia David

Missense3D-PPI predicts the impact of missense variants on protein-protein interfaces using structural data, showing improved sensitivity over previous methods.

Journal of Molecular Biology · Mar 24, 2023Peer-reviewedBioinformatics

Structure, function and variants analysis of the androgen-regulated TMPRSS2, a drug target candidate for COVID-19 infection

Alessia David, Tarun Khanna, Melina Beykou, Gordon Hanna, Michael J.E. Sternberg

The paper analyzes TMPRSS2 variants and their potential impact on SARS-CoV-2 infection, showing that some variants may affect protein structure and function, and that TMPRSS2 and ACE2 are co-expressed in the gastrointestinal tract.

bioRxiv · May 26, 2020 · PreprintBioinformatics