Author

Nicolle A. Rosa-Mercado

Johns Hopkins UniversityORCID 0000-0002-2158-2199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Elif S. Hearn· 1 shared Jesse RinehartiD· 1 shared JOAN ARGETSINGER STEITZiD· 1 shared Joshua T. ZimmeriD· 1 shared Juri RappsilberiD· 1 shared Kate L. ScholeiD· 1 shared Łukasz SzyrwieliD· 1 shared Maria ApostolidiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Elif S. Hearn

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2 papers

Recent·Most cited

SERBP1 is a master regulator of ribosome interactions

Nicolle A. Rosa-Mercado, Elif S. Hearn, Łukasz Szyrwiel, Kate L. Schole, Juri Rappsilber, Rachel Green

This study identifies SERBP1 as a regulator of ribosome interactions, showing its role in modulating factors involved in mRNA degradation, translational control, and ribosome quality control.

bioRxiv · Aug 27, 2026 · PreprintMolecular Biology

Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repression

Nicolle A. Rosa-Mercado, Joshua T. Zimmer, Maria Apostolidi, Jesse Rinehart, Matthew D. Simon, JOAN ARGETSINGER STEITZ

The paper shows hyperosmotic stress causes transcriptional repression but still leads to downstream-of-gene (DoG) transcripts, with Pol II interactome changes and Integrator complex disruption involved.

Molecular Cell · Jan 9, 2021Peer-reviewedMolecular Biology