Łukasz Szyrwiel

This study identifies SERBP1 as a regulator of ribosome interactions, showing its role in modulating factors involved in mRNA degradation, translational control, and ribosome quality control.

SILAC-Site directly measures phosphosite stoichiometries without enrichment, showing low stoichiometry for most phosphopeptides and correlating with direct detection.

Pho-Tip is a one-pot dephosphorylation method that improves the detection of low-abundant phosphorylated peptides in DIA phosphoproteomics data.

The paper benchmarks proteomics accuracy using a large-scale dataset, identifying systematic errors and providing a resource for method optimization and software evaluation.

The paper quantifies yeast cell responses to varying metal ions, revealing widespread proteomic and genetic impacts and common metal responsiveness properties.

The paper records proteomes for non-essential gene knock-outs in yeast to uncover principles of protein expression and annotate gene function.

The paper demonstrates improved proteomic depth using DIA-NN and FragPipe for dia-PASEF data, achieving higher sensitivity and quantification in complex samples.