Author

Hendrikus Jan Dubbink

Erasmus MCORCID 0000-0002-2160-5207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aitor Rodríguez‐CasanovaiD· 1 shared Alexander HoischeniD· 1 shared Alexandre HarléiD· 1 shared Alexis RapiniD· 1 shared Anes Hadjadj AouliD· 1 shared Ángel Díaz‐LagaresiD· 1 shared Anne‐Marie C. DingemansiD· 1 shared Bauke YlstraiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aitor Rodríguez‐CasanovaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Analytical Validation of a Pan-Cancer NGS Assay for In-House Liquid Biopsy Testing: An International Multicenter Study

Gaëlle Lescuyer, Alexandre Harlé, Hari Shankar Kumar, Pantelis Constantoulakis, Nicole Pfarr, Ellen Heitzer, Clémence Michon, Gianluca Russo, Ernst‐Jan M. Speel, Marie Piecyk, Marie Husson, Georgia Christopoulou, Eva-Maria Mayr, Mai-Lan Koppermann, Christophe Passot, , Lea Francoise Payen

This study validates a pan-cancer NGS assay for liquid biopsy testing across multiple centers, showing high sensitivity and specificity for detecting genomic alterations in cfDNA.

Journal of Molecular Diagnostics · Sep 25, 2025Peer-reviewedGenetic & Genomic Medicine

Clinical validation of Whole Genome Sequencing for cancer diagnostics

Paul Roepman, Ewart de Bruijn, Stef van Lieshout, Lieke Schoenmaker, Mirjam C. Boelens, Hendrikus Jan Dubbink, Willemina R.R. Geurts-Giele, Floris H. Groenendijk, Manon M. H. Huibers, Mariëtte E.G. Kranendonk, Margaretha G.M. Roemer, Kris G. Samsom, Marloes Steehouwer, Wendy W.J. de Leng, Alexander Hoischen, , Edwin P. J. G. Cuppen

This study validates whole genome sequencing as a reliable single assay for detecting various cancer mutations with high sensitivity and precision.

Journal of Molecular Diagnostics · May 6, 2021Peer-reviewedGenetic & Genomic Medicine