Author

Richard D. Ye

Chinese University of Hong KongORCID 0000-0002-2164-5620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Aijun LiuiD· 2 shared Yezhou LiuiD· 2 shared Weijia Zhang· 1 shared Yuanzhengyang Long· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersBiochemistry

Aijun LiuORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 16, 2025

Molecular insights into ligand recognition and signaling of GPR99/OXGR1

Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D. Ye

This study presents cryo-EM structures of GPR99/OXGR1 with oxoglutarate and LTE4, revealing distinct binding sites and signaling mechanisms.

DOI 10.1101/2025.08.16.670657

𝕏 PostBluesky

BiochemistrybioRxivFeb 3, 2024

Structural insights into agonist binding and activation of succinate receptor 1

Aijun Liu, Yezhou Liu, Weijia Zhang, Richard D. Ye

This study presents cryo-EM structures of SUCNR1-Gi complexes bound to succinate and epoxysuccinate, revealing key residues and structural changes involved in agonist binding and activation.

DOI 10.1016/j.celrep.2024.114381

𝕏 PostBluesky