Christiane Haffner

This study introduces modern human-specific amino acid substitutions into mice and human brain organoids, showing improved chromosome segregation fidelity in modern humans compared to Neandertals.

This study shows that DOT1L activity regulates AP lineage progression in the developing mouse neocortex by controlling metabolic programs and gene expression.

The paper introduces a robotic platform for automated microinjection into single cells in intact tissue, significantly increasing throughput and yield compared to manual methods.