Suhasa B. Kodandaramaiah

Coordinated Representational Drift Across the Mouse Cortex

The paper tracks spatial tuning changes in mouse cortex neurons over time and finds coordinated representational drift across different cortical regions.

Cortex-wide characterization of decision-making neural dynamics during spatial navigation

The paper characterizes decision-making neural dynamics during spatial navigation in mice by analyzing cortex-wide calcium dynamics across different paradigms.

ML-guided robotic microinjection of single neurons in human brain organoids

This paper introduces a robotic system for high-throughput single-cell manipulation in human brain organoids using vision guidance.

Cortex-Wide Cellular Imaging in Freely Locomoting Mice Using Cortex Camera Array Microscope (CortexCAM)

The paper introduces a mobile microscope system, CortexCAM, for imaging large areas of the mouse cortex during natural behaviors.

Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)

The paper introduces a miniaturized micro-camera array microscope (mini-MCAM) for wide-field calcium imaging in freely behaving mice, enabling cortex-wide neural activity monitoring.

Early and widespread engagement of the cerebellum during hippocampal epileptiform activity

The paper investigates cerebellar activity during seizures in epileptic mice, finding widespread and pre-ictal engagement of the cerebellum beyond motor-related areas.

Computer vision guided open-source active commutator for neural imaging in freely behaving animals

This paper introduces an open-source active commutator using computer vision to enable reliable long-term neural imaging in freely behaving mice without affecting neurophysiological signals.

Computer vision guided rapid and precise automated cranial microsurgeries in rodents

This paper introduces a computer vision-guided robot for performing rapid and precise cranial microsurgeries in rodents, reducing surgery time and training requirements.

Mesoscale Ca2+ imaging reveals networks of Purkinje cell dendritic and somatic modulation, with divergent roles of activity versus correlation during behavior

The paper uses Ca2+ imaging to study Purkinje cell networks in the cerebellum, revealing distinct dendritic and somatic activity patterns and their correlation dynamics during behavior.

Brain-wide neural recordings in mice navigating physical spaces enabled by a cranial exoskeleton

This paper introduces a cranial exoskeleton that enables mice to navigate physical spaces while recording brain-wide neural activity, achieving natural movement and performance comparable to free behavior.

A machine vision guided robot for fully automated embryonic microinjection

This paper describes a machine vision guided robot that automates microinjection in fruit fly and zebrafish embryos, achieving high throughput and comparable proficiency to human experts.

Distinct mesoscale cortical dynamics encode search strategies during spatial navigation

The paper identifies distinct cortical activation patterns during spatial navigation strategies in mice using mesoscale calcium dynamics.

Fully Desktop Fabricated Flexible Graphene Electrocorticography (ECoG) Arrays

This paper presents a fully desktop-fabricated flexible graphene ECoG array that can record brain activity in mice with long-term functionality and customizable electrode layouts.

3D morphometric analysis of mouse skulls using microcomputed tomography and computer vision

The paper analyzes mouse skull morphology using microCT and computer vision to compare wildtype and transgenic strains, finding limited morphological differences and significant dorsal bone thickness variations.

Polymer skulls with integrated transparent electrode arrays for cortex-wide opto-electrophysiological recordings

This paper introduces eSee-Shells, transparent polymer skulls with integrated electrode arrays for long-term multimodal neural recordings in mice.

Wide-field Calcium Imaging Reveals Widespread Changes in Cortical Connectivity Following Repetitive, Mild Traumatic Brain Injury in the Mouse

This study uses calcium imaging to show that repetitive mild traumatic brain injury in mice causes long-term changes in cortical functional connectivity without affecting cognitive or motor function.

Wide-Field Calcium Imaging of Dynamic Cortical Networks During Locomotion

The paper uses calcium imaging to study functional connectivity changes in the cerebral cortex during locomotion in mice, finding increased correlation and causality in premotor regions.

Miniaturized head-mounted device for whole cortex mesoscale imaging in freely behaving mice

This paper introduces a head-mounted microscope for whole-cortex mesoscale imaging in freely behaving mice and demonstrates its use in studying neural activity during various behaviors.

Robotic platform for microinjection into single cells in intact tissue

The paper introduces a robotic platform for automated microinjection into single cells in intact tissue, significantly increasing throughput and yield compared to manual methods.

Cortex-wide neural interfacing via transparent polymer skulls

This paper introduces See-Shells, transparent polymer skulls that enable long-term optical access to the mouse cortex for simultaneous monitoring and perturbation of neural activity across multiple regions.