Author

Aaron J. Knox

Morgan Adams FoundationORCID 0000-0002-2179-9961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adam L. GreeniD· 1 shared Gabrielle LinkiD· 1 shared Ilango BalakrishnaniD· 1 shared John A. DeSistoiD· 1 shared Rajeev VibhakariD· 1 shared Sujatha VenkataramaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Adam L. GreenORCID

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1 paper

Recent·Most cited

Cancer BiologyMolecular Cancer ResearchPeer-reviewedOct 18, 2024

PRMT5 maintains tumor stem cells to promote pediatric high-grade glioma tumorigenesis

John A. DeSisto, Ilango Balakrishnan, Aaron J. Knox…·Adam L. Green

This study identifies PRMT5 as essential for pediatric high-grade glioma growth by maintaining tumor stem cells, showing that its inhibition reduces self-renewal and improves survival in preclinical models.

4 citations

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