Adam L. Green

AURORA-MSI is an open-source multispectral imaging platform that enables excitation-resolved measurements of bioluminescence, luminescence decay, and chemical discrimination without photon-counting instrumentation.

This study evaluates ixazomib's efficacy against high-risk pediatric brain tumors, finding it cytotoxic but with limited CNS penetration.

This study evaluates combination therapy of CDK4/6 and MEK inhibitors in DMG models, finding survival benefits in GEM but not PDX models.

This study uses BioBombe to analyze gene process dependencies in cancer, identifying new therapeutic targets and drug candidates.

This paper identifies CD99 as a therapeutic target in K27M+DMGs, showing that a novel anti-CD99 antibody reduces tumor growth and enhances radiation efficacy in preclinical models.

This study examines how microbubble size, composition, and sonication points affect blood-brain barrier opening and sterile inflammatory response in mice.

This study identifies PRMT5 as essential for pediatric high-grade glioma growth by maintaining tumor stem cells, showing that its inhibition reduces self-renewal and improves survival in preclinical models.