Author

Rafael Maciel‐de‐Freitas

Instituto Oswaldo CruzORCID 0000-0002-2198-6492Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:large language model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ademir Jesus MartinsiD· 1 shared Alessandra Leda ValverdeiD· 1 shared Ana Caroline Silas RodriguesiD· 1 shared Anthony Albanese· 1 shared Anthony Daniel CakiD· 1 shared Ary A. HoffmanniD· 1 shared Carolaine da Silva de AraujoiD· 1 shared Charles J VörösmartyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperEcology

Ademir Jesus MartinsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Asking the Data: Conversational Interrogation of LC-MS/MS Proteomics Data Sets with an LLM Agent

Carolaine da Silva de Araujo, Milan S. G. Keirsebelik, Ana Caroline Silas Rodrigues, Alessandra Leda Valverde, Rafael Maciel‐de‐Freitas, Marília Zaluar P. Guimarães, Magno Junqueira

The paper introduces a conversational framework using an LLM agent to interrogate proteomics data sets, identifying issues in four LC-MS/MS datasets and demonstrating its feasibility in reanalyzing data.

bioRxiv · Oct 27, 2026 · PreprintBioinformatics

Wolbachia introgression in Rio de Janeiro remains at sub-optimal levels 30 months after its crash: challenges in the sustainability of wMel interventions for dengue control

Karine Pedreira Padilha, Gabriela A. Garcia, Rayane Teles-de-Freitas, Franck Jeannot Gnonhoue, Mariana Rocha David, Jéssica Corrêa-Antônio, Felipe de Oliveira, Luiz Paulo Brito, Luciana dos Santos Dias, Ademir Jesus Martins, Vincent Corbel, José Bento Pereira Lima, Gabriel Luz Wallau, Ary A. Hoffmann, Oswaldo Gonçalves Cruz, , Rafael Maciel‐de‐Freitas

This study assesses the long-term persistence of Wolbachia wMel in Rio de Janeiro 30 months after a population crash, finding suboptimal introgression levels and highlighting challenges in sustaining Wolbachia-based dengue control.

bioRxiv · Jul 29, 2025 · PreprintEcology

Forecasting Dengue Fever in Brazil Using Multimodal Data, Including Climate Data

David Danko, Charles J Vörösmarty, Anthony Daniel Cak, Fabio Corsi, Suraj J. Patel, John C Papciak, Heather Wells, Anthony Albanese, Christopher E. Mason, Rafael Maciel‐de‐Freitas, Dorottya Nagy‐Szakal, Niamh B. O’Hara

This paper introduces a dengue fever forecasting model for Brazil using multimodal data, achieving accurate monthly predictions up to 6 months ahead.

bioRxiv · Mar 12, 2024 · PreprintBioinformatics