Author

Benjamin J. Lang

Beth Israel Deaconess Medical CenterORCID 0000-0002-2205-8591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aaron M. NewmaniD· 1 shared Aashi Jain· 1 shared Alberto ValdeolivasiD· 1 shared Alexander ScholziD· 1 shared Andrew E. LambiD· 1 shared Andrew J. GentlesiD· 1 shared Aurélien de ReynièsiD· 1 shared Austin MeadowsiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aaron M. NewmanORCID

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Author profile →

2 papers

Recent·Most cited

Community assessment of methods to deconvolve cellular composition from bulk gene expression

Brian S. White, Aurélien de Reyniès, Aaron M. Newman, Joshua J. Waterfall, Andrew E. Lamb, Florent Petitprez, Yating Lin, Rongshan Yu, Martin E. Guerrero-Gimenez, Sergii Domanskyi, Gianni Monaco, Verena Chung, Jineta Banerjee, Daniel S. Derrick, Alberto Valdeolivas, , Andrew J. Gentles

The paper evaluates deconvolution methods for inferring immune infiltration from bulk gene expression using a DREAM Challenge, finding that some community-contributed methods, especially deep learning-based ones, perform well.

Nature Communications · Aug 27, 2024Peer-reviewedBioinformatics

SCAND1 suppresses CDC37 gene transcription by repressing MZF1

Takanori Eguchi, Thomas L. Prince, Manh Tien Tran, Chiharu Sogawa, Benjamin J. Lang, Stuart K. Calderwood

The paper identifies SCAND1 as a tumor suppressor that negatively regulates CDC37 gene transcription by inhibiting MZF1 in prostate cancer.

bioRxiv · Apr 24, 2019 · PreprintMolecular Biology