Daniel S. Derrick

This study identifies HIF1A as a key mediator of OSM-induced collective epithelial migration, linking cytokine signaling to metabolic and immune pathways in breast cancer.

This study identifies immune mimicry in breast cancer cells, where neoplastic cells express leukocyte receptors, enhancing tumor aggressiveness and therapy resistance.

This study investigates how combinations of EGF, OSM, and TGFB cytokines synergistically drive cell motility through CXCR2 chemotaxis and CREB activation in MCF10A cells.

The paper evaluates deconvolution methods for inferring immune infiltration from bulk gene expression using a DREAM Challenge, finding that some community-contributed methods, especially deep learning-based ones, perform well.

The paper presents a LINCS Microenvironment perturbation dataset cataloging transcriptional, proteomic, epigenomic, and phenotypic responses of MCF10A cells to six ligands, enabling integrative analysis of molecular and phenotypic changes.