Chloe He

ASLAN identifies regions of the human genome missing from GRCh38 and finds new genetic diversity hotspots by analyzing unmapped reads from nuclear families.

The paper analyzes contamination in whole genome sequencing data from 1,000 families, identifying bacterial, viral, and computational sources that affect sequencing accuracy.

The paper analyzes whole genome sequences of families to study the human blood DNA virome, finding evidence of household transmission and de novo viral integration.

The paper introduces an open-source program using Python and OpenCV to automate the calibration and size measurement of objects in bright-field microscopy images.