Anna‐Leena Sirén

This study examines the ultrastructural changes in active zones of RIM1α knock-out mice compared to wild-type, revealing altered synaptic vesicle organization and architecture.

The paper develops a method for 3D-dSTORM imaging of mouse brain sections to analyze presynaptic active zones, finding differences in Bassoon cluster size and density across hippocampal regions.

The paper investigates presynaptic homeostatic potentiation (PHP) in Drosophila melanogaster, finding that AZs compact rather than enlarge, increasing protein density without changing Brp copy numbers.