Achmed Mrestani

This study identifies Rab3 as a mediator of cAMP-induced presynaptic plasticity and shows its necessity for olfactory learning in Drosophila.

This study shows that overexpression of the Drosophila Bchs gene, an ortholog of human WDFY3, causes neural developmental issues in both neurons and glial cells, mirroring human neurodevelopmental disorders.

The paper uses endogenous tagging to study Unc-13 nanocluster reorganization during presynaptic homeostatic potentiation in Drosophila.

The paper identifies altered gene expression patterns in 15q13.3 microdeletion carriers, showing dysregulation of genes involved in brain development and contributing to phenotypic variability.

The paper measures channel opening durations in nicotinic acetylcholine receptors (nAChRs) by recording single-molecule currents and finds that agonist binding at specific sites determines opening durations and burst patterns.

The paper develops a method for 3D-dSTORM imaging of mouse brain sections to analyze presynaptic active zones, finding differences in Bassoon cluster size and density across hippocampal regions.

The paper investigates presynaptic homeostatic potentiation (PHP) in Drosophila melanogaster, finding that AZs compact rather than enlarge, increasing protein density without changing Brp copy numbers.