Colitis-primed circulating T cells drive small intestinal barrier function through Nod2, microbiota and myosin light chain kinase-dependent mechanisms
Arthur Mauduit, Talal Nabhani, Luisa Morelli…·Ziad Al Nabhani
This study shows that colitis-primed T cells affect small intestinal barrier function via Nod2, microbiota, and MLCK mechanisms, with distinct roles for hematopoietic and non-hematopoietic Nod2.