Yasutomi Higashikuni

The paper develops REFLEX and HUNTERuni-seq to identify perivascular angiogenic macrophages (PVAMs) that deliver VEGF-A to endothelial cells, showing physical contact is critical for effective signaling.

This paper develops a deep learning model to estimate patient age and sex from chest X-rays, finding that CXR age correlates with cardiovascular aging and disease outcomes.

The paper introduces a programmable read-write head for genomic DNA at single-nucleotide resolution, enabling scalable and robust computing and memory operations in living cells.