Author

Shipra Malhotra

Fox Chase Cancer CenterORCID 0000-0002-2234-191XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Ahmad NajafianiD· 1 shared Alejandro Crespo· 1 shared Andreas EversiD· 1 shared Benjamin E. BlassiD· 1 shared Christopher S Parry· 1 shared Daniel KühniD· 1 shared Elena Bondarenko· 1 shared Erica A. GolemisiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Ahmad NajafianORCID

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2 papers

Recent·Most cited

Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

Mariam Ahmed Fouad, Christopher S Parry, Sven A. Miller, Shipra Malhotra, Glenn A. R. Doyle, Ezra Shimabenga, Mashhura Nurilloeva, Elena Bondarenko, Grigorii V. Andrianov, Wayne Childers, Benjamin E. Blass, Petr B. Makhov, Johnathan R. Whetstine, Margie L. Clapper, Erica A. Golemis, John Karanicolas

The paper identifies small molecules that stabilize and restore function to missense-mutated VHL proteins in kidney cancer cells.

bioRxiv · May 29, 2026 · PreprintBiochemistry

SUMO - In Silico Sequence Assessment Using Multiple Optimization Parameters

Andreas Evers, Shipra Malhotra, Wolf-Guido Bolick, Ahmad Najafian, Maria Borisovska, Shira Warszawski, Yves Fomekong‐Nanfack, Daniel Kühn, Friedrich Rippmann, Alejandro Crespo, Vanita D. Sood

The paper introduces a computational method to assess and rank antibody and VHH sequences based on developability, diversity, and optimization potential using in silico analysis.

bioRxiv · Nov 19, 2022 · PreprintBioinformatics