Author

Ciro A. Cubillas

Washington University in St. LouisORCID 0000-0002-2238-8048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Abhinav DiwaniD· 1 shared Adelita D. MendozaiD· 1 shared Chen Zhao· 1 shared Daniel Herrera· 1 shared Daniel L. SchneideriD· 1 shared Hanwenheng LiuiD· 1 shared John Edwards· 1 shared John T. MurphyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Abhinav DiwanORCID

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1 paper

Recent·Most cited

Zinc excess promotes lysosome remodeling by activating HLH-30/TFEB through the action of the high zinc sensor HIZR-1.

Ciro A. Cubillas, Hanwenheng Liu, Krupa Deshmukh, Adelita D. Mendoza, Daniel L. Schneider, Daniel Herrera, Chen Zhao, John T. Murphy, John Edwards, Abhinav Diwan, Kerry Kornfeld

The paper identifies a zinc-regulated genetic pathway in C. elegans that activates lysosome remodeling through HIZR-1 and HLH-30/TFEB to enhance zinc detoxification.

bioRxiv · Feb 24, 2026 · PreprintGenetics