Jay S. Coggan

The paper develops a molecular model of the aging brain's metabolic system, identifies key disruptions, and proposes interventions to restore metabolic flexibility and neuronal function.

The paper develops a method to generate geometrically realistic and watertight neuronal manifolds from morphological data for in silico simulations.

The paper compares dendritic architecture in human and mice neuronal networks, finding that human pyramidal cells have greater dendritic complexity, contributing to increased network complexity despite lower neuron density.

Ultraliser creates high-fidelity 3D models of neuroscientific structures for in silico simulations, enabling detailed structural analysis and scalable experiments.