Author

Julian D. C. Serna

Universidade de São PauloORCID 0000-0002-2285-5769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alicia Juliana KowaltowskiiD· 3 shared Camille C. Caldeira da SilvaiD· 2 shared Anna RaffaelloiD· 1 shared Donato D’AngeloiD· 1 shared Éverton Lopes VogtiD· 1 shared Georgia Ohya· 1 shared Heberty Tarso FacundoiD· 1 shared Henrique CamaraiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersPhysiology

Alicia Juliana KowaltowskiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Caloric Restriction Promotes Ischemia/Reperfusion Cardioprotection Through Increased Mitochondrial Na+/Ca2+ Exchange

Maiara Queiroz, Camille C. Caldeira da Silva, Éverton Lopes Vogt, Marcos A.E. Cruz, Julian D. C. Serna, Luiz Roberto Grassmann Bechara, Julio Cesar Batista Ferreira, Heberty Tarso Facundo, Alicia Juliana Kowaltowski

This study shows caloric restriction enhances mitochondrial Na+/Ca2+ exchange, reducing oxidative stress and improving cardiac recovery after ischemia/reperfusion injury.

bioRxiv · Sep 25, 2026 · PreprintBiochemistry

YME1L-dependent regulation of mitochondrial Ca2+ transport: a role for mitochondrial uptake protein 1 (MICU1) in nutrient sensing

Julian D. C. Serna, Donato D’Angelo, Georgia Ohya, Rosario Rizzuto, Alicia Juliana Kowaltowski, Anna Raffaello

This study shows that YME1L-dependent degradation of MICU1 regulates mitochondrial Ca2+ uptake in response to nutrient changes, linking metabolic signals to mitochondrial function.

bioRxiv · Dec 14, 2025 · PreprintPhysiology

Mitochondrial ATP-Sensitive K+ Channels (MitoKATP) Regulate Brown Adipocyte Differentiation and Metabolism

Osvaldo Rodrigues Pereira, Julian D. C. Serna, Camille C. Caldeira da Silva, Henrique Camara, Sean David Kodani, William T. Festuccia, Yu‐Hua Tseng, Alicia Juliana Kowaltowski

This study shows that MitoKATP channels regulate brown adipocyte differentiation and metabolism, impacting thermogenesis through effects on oxygen consumption and cellular respiration.

bioRxiv · Jan 21, 2025 · PreprintPhysiology