Yu‐Hua Tseng

The paper identifies distinct adipocyte subsets in human white adipose tissue with different metabolic profiles and links TSHZ3 to their regulation and metabolic disease associations.

The paper shows cold acclimation increases n-3 HUFAs in the liver, reducing steatosis by altering lipid composition and metabolism.

MEBOCOST infers metabolite-mediated cell communications from single-cell RNA-seq data, identifying known and novel interactions in mouse brown adipose tissue.

This study shows that MitoKATP channels regulate brown adipocyte differentiation and metabolism, impacting thermogenesis through effects on oxygen consumption and cellular respiration.

The paper identifies linoleic acid diols that inversely associate with BMI and activate adipocyte calcium fluxes using a novel tool called ScreenDMT.

This study uses single-cell RNA sequencing to identify brown fat precursors and demonstrates their in vitro differentiation into functional brown adipocytes.

The paper analyzes intercellular communication in brown adipose tissue using single-cell transcriptomics and identifies temperature-regulated signaling interactions.

This study identifies the cellular origins of perivascular adipose tissue using single-cell transcriptomics, fate mapping, and adipogenesis assays, revealing fibroblastic and smooth muscle progenitors.

The paper identifies a new source of cold-induced brown adipocytes, specifically vascular smooth muscle-derived progenitors expressing TRPV1.

The paper identifies cold-induced neuroimmune cells that contribute to adipose innervation and nerve remodeling under noradrenergic stimulation.