Author

Xiaobo Zhou

The University of Texas Health Science Center at HoustonORCID 0000-0002-2305-2255Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiaobo zhou6 papers · The University of Texas Health Science Center at Houston

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Liyu HuangiD· 2 shared J Liu· 1 shared Jiajin ZhangiD· 1 shared Jiangpeng WeiiD· 1 shared Jianguo WeniD· 1 shared Kexin HuangiD· 1 shared Li XiaoiD· 1 shared Sayed‐Rzgar HosseiniiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioinformatics

Liyu HuangORCID

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Author profile →

3 papers

Recent·Most cited

Identification and Characterization of Metastasis-initiating cells

Sijia Wu, Jiangpeng Wei, Xin Liu, Jiajin Zhang, Jianguo Wen, Liyu Huang, Xiaobo Zhou

This paper introduces scMIC, a computational framework for identifying metastasis-initiating cells from single-cell data, validated across multiple cancer types and datasets.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics

Benchmarking algorithms for RNA velocity inference

Kexin Huang, Yu Zhou, Tiangang Wang, Li Xiao, Xinlong Zhao, Xi Liu, Liyu Huang, Xiaobo Zhou, J Liu

This study benchmarks 29 RNA velocity algorithms across simulated and real scRNA-seq datasets, highlighting performance variations and practical constraints.

bioRxiv · Jan 3, 2026 · PreprintBioinformatics

Predicting anti-cancer drug synergy using extended drug similarity profiles

Sayed‐Rzgar Hosseini, Xiaobo Zhou

This paper introduces CCSynergy, a deep learning framework for predicting anti-cancer drug synergy using extended drug similarity profiles, achieving superior accuracy and context-generalizability.

Briefings in Bioinformatics · Dec 2, 2022Peer-reviewedBioinformatics